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The Physiological Function Of Nickel

wallpapers News 2021-01-21
Nickel is a transition metal element with element symbol Ni, located in group VIII of the fourth period, with atomic number 28. Nickel is a silver-white metal with good mechanical strength and ductility. It is insoluble in water and has strong corrosion resistance to acids and alkalis, but it is easily soluble in dilute nitric acid and aqua regia. High temperature resistance, melting point 1455 °C, boiling point 2730 °C. The density is 8.902g/cm³. It can be used to make currency, etc. It can be plated on other metals to prevent rust.
 
Physiological function
 
Nickel is an essential life element for the human body, and the content in the human body is extremely small. Under normal circumstances, the body of an adult contains about 10 mg of nickel, and the normal concentration in the blood is 0.11μgNi.ml-1. Nickel is involved in the role of hormones and the structural stability of biological macromolecules and in the process of metabolism. The daily requirement of the human body for nickel is 0.3mg. Nickel deficiency can cause diabetes, anemia, liver cirrhosis, uremia, renal failure, abnormal liver lipid and phospholipid metabolism and other diseases.
 
Nickel is also the most common allergenic metal. About 20% of people are allergic to nickel ions. The number of female patients in allergic groups is higher than that of male patients. When in contact with the human body, nickel ions can penetrate into the skin through pores and sebaceous glands. Go inside, causing skin allergies and inflammation. The clinical manifestations are itching, papular or papular vesicular dermatitis and eczema, accompanied by lichenification. Once sensitization symptoms appear, nickel allergy can last indefinitely.
 
Even more serious is the poisoning caused by excessive nickel intake. Ingestion of 250mg of soluble nickel per day by the human body can cause poisoning. The specific symptoms are dermatitis, respiratory organ disorders and respiratory cancer. According to animal experiments, chronic over-intake or over-exposure can lead to degeneration of myocardium, brain, lung, liver and kidney.

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